Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824405 | 0.89 | TACR1 (0.70) | TACR1 | |
| SCHEMBL8480232 | 0.87 | TACR1 (0.66) | TACR1 | |
| SCHEMBL6100165 | 0.87 | TACR1 (0.66) | TACR1 | |
| SCHEMBL7816243 | 0.87 | TACR1 (0.66) | TACR1 | |
| SCHEMBL7815972 | 0.87 | TACR1 (0.66) | TACR1 | |
| SCHEMBL8478957 | 0.87 | TACR1 (0.65) | TACR1 | |
| SCHEMBL7823721 | 0.87 | TACR1 (0.65) | TACR1 | |
| SCHEMBL6098703 | 0.87 | TACR1 (0.65) | TACR1 | |
| SCHEMBL8480292 | 0.86 | TACR1 (0.67) | TACR1 | |
| SCHEMBL7816140 | 0.86 | TACR1 (0.67) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176144-B1 | N-triazolylmethyl-piperazine derivatives as neurokinine receptor-antagonists | SOLVAY PHARM GMBH (DE) | 2003-07-09 | — | — | EP | disclosed |
| US-6407106-B1 | FOR THERAPY OF INFLAMMATORY DISTURBANCES OF THE GASTROINTESTINAL TRACT | SOLVAY PHARMACEUTICALS GMBH (DE) | 2002-06-18 | — | — | US | disclosed |
| EP-1176144-A1 | N-triazolylmethyl-piperazine derivatives as neurokinine receptor-antagonists | Solvay Pharmaceuticals GmbH (DE) | 2002-01-30 | — | — | EP | disclosed |