Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | ESR1 | P03372 | 7/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.67 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088627 | 0.91 | ERAP1 (0.83) | ERAP1NPC1ESR1ESR2HSD17B3 | |
| SCHEMBL7113502 | 0.86 | ERAP1 (0.75) | ERAP1NPC1ESR1ESR2HSD17B3 | |
| SCHEMBL7460755 | 0.86 | ERAP1 (0.55) | ERAP1NPC1ESR1ESR2HSD17B3 | |
| SCHEMBL1608015 | 0.86 | ERAP1 (1.00) | ERAP1NPC1ESR1ESR2HSD17B3 | |
| SCHEMBL8118679 | 0.84 | ERAP1 (0.53) | ERAP1NPC1ESR1ESR2HSD17B3 | |
| SCHEMBL5427914 | 0.84 | NPC1 (1.00) | ERAP1NPC1ESR1ESR2HSD17B3 | |
| SCHEMBL13486861 | 0.84 | ERAP1 (0.71) | ERAP1NPC1ESR1ESR2HSD17B3 | |
| SCHEMBL5424524 | 0.83 | ERAP1 (0.56) | ERAP1NPC1ESR1ESR2HSD17B3 | |
| SCHEMBL13713069 | 0.83 | ERAP1 (0.52) | ERAP1NPC1ESR1ESR2HSD17B3 | |
| SCHEMBL4798266 | 0.83 | ERAP1 (0.75) | ERAP1NPC1ESR1ESR2HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |