Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.41 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20912033 | 0.86 | GRIA1 (0.47) | ADORA3SRCABCC1KDM4EALDH1A1 | |
| SCHEMBL7127079 | 0.84 | ABCC1 (0.45) | ADORA3SRCABCC1KDM4EALDH1A1 | |
| SCHEMBL4225129 | 0.82 | PARP1 (0.42) | ADORA3ABCC1KDM4EALDH1A1HPGD | |
| SCHEMBL20911692 | 0.80 | SRC (0.51) | ADORA3SRCKDM4EALDH1A1HPGD | |
| SCHEMBL20911817 | 0.79 | SRC (0.48) | ADORA3SRCKDM4EALDH1A1HPGD | |
| SCHEMBL20898390 | 0.79 | SRC (0.48) | ADORA3SRCKDM4EALDH1A1HPGD | |
| SCHEMBL4221425 | 0.78 | ABCC1 (0.52) | ABCC1ALDH1A1SMN1; SMN2ABCB1MAPT | |
| SCHEMBL8819526 | 0.78 | SRC (0.64) | ADORA3SRCKDM4EALDH1A1HPGD | |
| SCHEMBL20911691 | 0.78 | SRC (0.48) | SRCHTTMAPTLMNAGAA | |
| SCHEMBL20912335 | 0.74 | SRC (0.49) | ADORA3SRCKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | CAO JINGRONG (US) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | GSK3B, GSK3A, GSKIP | ADORA3 673/4885SRC 277/4885ABCC1 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.