Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.77 |
| ▸ | RAB9A | P51151 | 4/20 | 0.77 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.77 |
| ▸ | MMP13 | P45452 | 2/20 | 0.72 |
| ▸ | SCD | O00767 | 3/20 | 0.71 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | STAT1 | P42224 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.63 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.61 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14807297 | 0.91 | SCD (0.71) | NPC1RAB9AMCL1MMP13SCD | |
| SCHEMBL16562175 | 0.89 | NPC1 (0.79) | NPC1RAB9AMCL1MMP13SCD | |
| SCHEMBL4909703 | 0.89 | NPC1 (0.71) | NPC1RAB9AMCL1MMP13SCD | |
| SCHEMBL26034899 | 0.88 | NPC1 (0.77) | NPC1RAB9AMCL1MMP13SCD | |
| SCHEMBL2187627 | 0.88 | NPC1 (0.80) | NPC1RAB9AMCL1MMP13SCD | |
| SCHEMBL23926499 | 0.88 | SCD (0.88) | NPC1RAB9AMCL1MMP13SCD | |
| SCHEMBL2191669 | 0.87 | NPC1 (1.00) | NPC1RAB9AMCL1MMP13SCD | |
| SCHEMBL23926524 | 0.87 | NPC1 (0.71) | NPC1RAB9AMCL1MMP13SCD | |
| SCHEMBL31219313 | 0.87 | NPC1 (0.71) | NPC1RAB9AMCL1MMP13SCD | |
| SCHEMBL12095405 | 0.86 | NPC1 (0.78) | NPC1RAB9AMCL1MMP13SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | SANKYO COMPANY, LIMITED (JP) | 2003-07-17 | — | — | US | disclosed |
| EP-1277729-A1 | PPAR (GAMMA) MODULATORS | Sankyo Company, Limited (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | PPARG, PPARA, PPARD | NPC1 1152/4885RAB9A 1179/4885MCL1 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.