Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQLE | Q14534 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19850534 | 0.92 | SQLE (0.58) | SQLESMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL15975345 | 0.91 | SQLE (0.59) | SQLESMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL11859933 | 0.89 | SQLE (0.53) | SQLESMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL11859938 | 0.89 | SQLE (0.53) | SQLESMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL2010370 | 0.89 | SQLE (0.47) | SQLEKMT2ALMNAMEN1HSD17B10 | |
| SCHEMBL2010368 | 0.89 | SQLE (0.47) | SQLEKMT2ALMNAMEN1HSD17B10 | |
| SCHEMBL28281532 | 0.89 | SQLE (0.47) | SQLEKMT2ALMNAMEN1HSD17B10 | |
| SCHEMBL1828506 | 0.87 | SQLE (0.52) | SQLESMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL1828504 | 0.87 | SQLE (0.52) | SQLESMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL16046466 | 0.87 | SQLE (0.52) | SQLESMN1; SMN2ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004093995-A2 | USE OF ANTIOXIDANTS TO TREAT BONE LOSS DISORDERS | ST GEORGE'S ENTERPRISES LIMITED (GB) | 2004-11-04 | — | — | WO | disclosed |