Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | RORC | P51449 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124300 | 0.97 | MAPT (0.55) | MAPTKMT2ARORCSMN1; SMN2MEN1 | |
| SCHEMBL7125980 | 0.97 | MAPT (0.55) | MAPTKMT2ARORCSMN1; SMN2MEN1 | |
| SCHEMBL7120551 | 0.96 | PPARG (0.55) | MAPTKMT2ARORCSMN1; SMN2MEN1 | |
| SCHEMBL7130317 | 0.96 | MAPT (0.60) | MAPTKMT2ARORCSMN1; SMN2MEN1 | |
| SCHEMBL7125943 | 0.93 | PPARG (0.56) | MAPTKMT2ARORCSMN1; SMN2MEN1 | |
| SCHEMBL7130309 | 0.93 | PPARG (0.56) | MAPTKMT2ARORCSMN1; SMN2MEN1 | |
| SCHEMBL7128935 | 0.93 | MAPT (0.59) | MAPTKMT2ARORCSMN1; SMN2MEN1 | |
| SCHEMBL7132440 | 0.92 | MAPT (0.58) | MAPTKMT2ARORCSMN1; SMN2MEN1 | |
| SCHEMBL7132342 | 0.92 | MAPT (0.58) | MAPTKMT2ARORCSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7121797 | 0.92 | PPARG (0.55) | MAPTKMT2ARORCSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1440383-A | PPAR gamma modulators | SANKYO CO (JP) | 2003-09-03 | — | — | CN | disclosed |
| EP-1277729-A1 | PPAR (GAMMA) MODULATORS | Sankyo Company, Limited (JP) | 2003-01-22 | — | — | EP | disclosed |