SCHEMBL7129231

SCHEMBL7129231

COC(=O)C1CCCCN1C(=O)c1cccc(C(=O)N2CCCCC2C(=O)OC)c1

nearest known ligand 0.81

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.58
LOX P28300 1/20 0.58
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
PDK2 Q15119 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14905825 0.91 LOX (0.56) KMT2ALOXNPC1RAB9APDK2
SCHEMBL3579235 0.90 NPC1 (0.57) KMT2ALOXNPC1RAB9APDK2
SCHEMBL3579233 0.90 NPC1 (0.57) KMT2ALOXNPC1RAB9APDK2
SCHEMBL10721062 0.88 KMT2A (0.60) KMT2ANPC1RAB9APDK2
SCHEMBL12569875 0.88 LOX (0.58) KMT2ALOXPDK2
SCHEMBL12261957 0.87 POLB (0.53) KMT2ALOXNPC1RAB9A
SCHEMBL24435015 0.86 KMT2A (0.59) KMT2ALOXNPC1RAB9APDK2
SCHEMBL1762519 0.86 KMT2A (0.59) KMT2ALOXNPC1RAB9APDK2
SCHEMBL9871506 0.86 KMT2A (0.59) KMT2ALOXNPC1RAB9APDK2
SCHEMBL12546030 0.85 KMT2A (0.55) KMT2ALOXPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US claimed
EP-1149877-B1 Decolorizable ink composition and ink jet printer using the ink composition RICOH KK (JP) 2003-06-11 EP disclosed
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US disclosed
US-20020175982-A1 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2002-11-28 US disclosed
EP-1149877-A1 Decolorizable ink composition and ink jet printer using the ink composition Ricoh Company, Ltd. (JP) 2001-10-31 EP disclosed
US-4665410-A THERMOGRAPHY RICOH COMPANY, LTD. (JP) 1987-05-12 US disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed