SCHEMBL712932

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10206627	0.93	CYP3A4 (0.46)	CYP3A4PDGFRBPDGFRAPRMT5PDE4A
	SCHEMBL10206607	0.92	CYP3A4 (0.51)	CYP3A4PDGFRBPDGFRAPRMT5PDE4A
	SCHEMBL2668133	0.90	CYP3A4 (0.47)	CYP3A4PDGFRBPDGFRAPRMT5MAPT
	SCHEMBL10206608	0.89	SYK (0.46)	CYP3A4PRMT5PDE4APDE4BPDE4C
	SCHEMBL711187	0.89	CYP3A4 (0.46)	CYP3A4PDGFRBPDGFRAPRMT5PDE4A
	SCHEMBL10206615	0.87	IKBKB (0.47)	CYP3A4PRMT5MAPTPDE4APDE4B
	SCHEMBL711485	0.86	PDE2A (0.52)	PDGFRBPDGFRAMAPTKDM4EMAPK1
	SCHEMBL9071887	0.85	CYP3A4 (0.51)	CYP3A4PRMT5PDE4APDE4BPDE4C
	Trifluoroacetic Acid SCHEMBL711595	0.85	LRRK2 (0.43)	CYP3A4PDE4APDE4BPDE4CPDE4D
	SCHEMBL9071848	0.85	CYP3A4 (0.42)	CYP3A4PDGFRBPDGFRAPRMT5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.