SCHEMBL7129943

SCHEMBL7129943

C=C(C)C(=O)OC.C=C(CC=CC(=O)O)C(=O)OCCCC

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
HCAR2 Q8TDS4 4/20 0.44
ALDH1A1 P00352 3/20 0.40
ATM Q13315 1/20 0.38
HPGD P15428 1/20 0.36
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
THRB P10828 1/20 0.36
MAPT P10636 2/20 0.34
RAB9A P51151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
PTPN1 P18031 1/20 0.32
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11356740 0.95 TSHR (0.56) TSHRHCAR2ALDH1A1POLBAPEX1
SCHEMBL7739132 0.92 TSHR (0.54) TSHRHCAR2ALDH1A1ATMHPGD
SCHEMBL9818331 0.92 TSHR (0.47) TSHRHCAR2ALDH1A1ATMHPGD
SCHEMBL9462802 0.91 TSHR (0.43) TSHRHCAR2ALDH1A1ATMHPGD
SCHEMBL313840 0.90 HCAR2 (0.53) TSHRHCAR2ALDH1A1ATMHPGD
SCHEMBL3400634 0.90 TSHR (0.60) TSHRHCAR2ALDH1A1POLBAPEX1
SCHEMBL10940121 0.90 TSHR (0.51) TSHRHCAR2ALDH1A1ATMHPGD
SCHEMBL11346702 0.89 TSHR (0.46) TSHRHCAR2ALDH1A1ATMHPGD
SCHEMBL8058643 0.89 TSHR (0.46) TSHRHCAR2ALDH1A1ATMHPGD
Styrene SCHEMBL9147646 0.88 TDP1 (0.40) TSHRHCAR2ALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112048042-A Reactive nitrogen phosphorus-graphene composite flame retardant modified acrylate and preparation method thereof 王康 2020-12-08 CN claimed
CN-112048042-A Reactive nitrogen phosphorus-graphene composite flame retardant modified acrylate and preparation method thereof 王康 2020-12-08 CN disclosed
US-6660457-B1 Method of forming conductive pattern KANSAI PAINT CO., LTD. (JP) 2003-12-09 US disclosed
EP-0578091-B1 Resin composition for sealing and semiconductor apparatus covered with the sealing resin composition CANON KK (JP) 1998-09-02 EP disclosed
US-5397401-A Mixtures of thermoplastic and thermosetting resins, styrene, acrylic ester polymers, solar cells CANON KABUSHIKI KAISHA (JP) 1995-03-14 US disclosed
EP-0578091-A2 Resin composition for sealing and semiconductor apparatus covered with the sealing resin composition CANON KABUSHIKI KAISHA (JP) 1994-01-12 EP disclosed
US-4929527-A DARK CHARGE RETAINING PROPERTIES FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US disclosed
US-4753708-A BLEND OF OLEFIN POLYMER, ACRYLIC RESIN AND BLOCK COPOLYMER OF OLEFIN, ACRYLIC SEGMENTS ROHM GMBH (DE) 1988-06-28 US disclosed