Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SAT1 | P21673 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL3558785 | 1.00 | — | — | |
| Diethylamine SCHEMBL2698 | 1.00 | — | — | |
| Diethylamine SCHEMBL7368833 | 1.00 | — | — | |
| Diethylamine SCHEMBL3520371 | 0.94 | — | — | |
| Diethylamine SCHEMBL21980959 | 0.94 | — | — | |
| Diethylamine SCHEMBL5051715 | 0.94 | — | — | |
| Diethylamine SCHEMBL21585568 | 0.94 | — | — | |
| Diethylamine SCHEMBL21585566 | 0.94 | — | — | |
| Diethylamine SCHEMBL9289074 | 0.94 | TP53 (0.89) | TP53CYP2C19MEN1GLAKMT2A | |
| Diethylamine SCHEMBL1514723 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437079-A | The process system of diethylamine and triethylamine is recycled from waste water | SHANDONG QILU PETROCHEMICAL ENG CO LTD | 2019-11-12 | — | — | CN | disclosed |
| EP-3464248-A1 | 3-OXO-2,6-DIPHENYL-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES | Bayer Pharma Aktiengesellschaft (DE) | 2019-04-10 | — | — | EP | disclosed |
| CN-109279744-A | A kind of release agent and method separating petroleum from petroleum greasy filth | 西安蓝达瑞新能源有限公司 | 2019-01-29 | — | — | CN | disclosed |
| WO-2017202816-A1 | 3-OXO-2,6-DIPHENYL-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-30 | — | — | WO | disclosed |
| CN-101935045-B | Electrofax tinter additive, toner, developer, formation method and device | RICOH CO., LTD. (JP) | 2016-01-27 | — | — | CN | disclosed |
| CN-102173545-B | Oily sludge thermochemical separating agent and using method thereof | UNIV YULIN | 2012-10-03 | — | — | CN | disclosed |
| CN-102173545-A | Oily sludge thermochemical separating agent and using method thereof | UNIV YULIN | 2011-09-07 | — | — | CN | disclosed |
| CN-101935045-A | External additive for electrophotographic toner, toner, developer and image forming method and apparatus | RICOH KK | 2011-01-05 | — | — | CN | disclosed |
| CN-1495548-A | Electrophotographic toner external additive, toner, developer, image forming method and apparatus | ������������ʽ���� | 2004-05-12 | — | — | CN | disclosed |
| EP-1325337-A2 | A METHOD FOR THE QUANTITATIVE DETERMINATION OF ONE OR MORE COMPOUNDS | Amersham Biosciences AB (SE) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002029414-A2 | A METHOD FOR THE QUANTITATIVE DETERMINATION OF ONE OR MORE COMPOUNDS | AMERSHAM BIOSCIENCES AB (SE) | 2002-04-11 | — | — | WO | disclosed |
| US-6284432-B1 | COAT PROPERTY, HAS NOT SPECIAL COLOR UNEVENNESS AND CONTRAST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-09-04 | — | — | US | disclosed |
| US-5364977-A | Chemical stabilization and powder processing | NIPPON SODA CO., LTD. (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0606632-A1 | Pigment compounds and application thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-07-20 | — | — | EP | disclosed |
| US-4054604-A | MICROBIOCIDES, HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-3981868-A | MICROBIOCIDES, HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1976-09-21 | — | — | US | disclosed |