SCHEMBL7130857

SCHEMBL7130857

Cc1cccc(C(=O)N2CCN(C(=O)c3cccc(C)c3)CC2)c1

nearest known ligand 0.83

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.83
HTT P42858 1/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
GABRD O14764 1/20 0.66
GABRA1 P14867 1/20 0.66
GABRB1 P18505 1/20 0.66
GABRA5 P31644 1/20 0.66
GABRA3 P34903 1/20 0.66
GABRA2 P47869 1/20 0.66
GABRB2 P47870 1/20 0.66
GABRA4 P48169 1/20 0.66
KDM4E B2RXH2 1/20 0.63
ALDH1A1 P00352 1/20 0.62
TP53 P04637 1/20 0.62
HSD11B1 P28845 1/20 0.61
MGLL Q99685 1/20 0.61
GBA1 P04062 1/20 0.59
GPR183 P32249 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14238822 1.00 HPGD (0.83) HPGDHTTL3MBTL1GABRDGABRA1
SCHEMBL8360507 0.93 HPGD (0.73) HPGDHTTL3MBTL1GABRDGABRA1
SCHEMBL12563716 0.93 HPGD (0.73) HPGDHTTL3MBTL1GABRDGABRA1
SCHEMBL1753626 0.93 HPGD (0.97) HPGDHTTL3MBTL1GABRDGABRA1
SCHEMBL2667152 0.93 HPGD (0.90) HPGDHTTL3MBTL1GABRDGABRA1
SCHEMBL19709510 0.92 HPGD (0.71) HPGDHTTL3MBTL1GABRDGABRA1
SCHEMBL17320467 0.92 HPGD (0.71) HPGDHTTL3MBTL1GABRDGABRA1
SCHEMBL12969 0.91 HPGD (1.00) HPGDHTTL3MBTL1GABRDGABRA1
SCHEMBL10174633 0.91 HPGD (1.00) HPGDHTTL3MBTL1GABRDGABRA1
SCHEMBL10195744 0.89 HPGD (0.68) HPGDHTTL3MBTL1GABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US claimed
EP-1149877-B1 Decolorizable ink composition and ink jet printer using the ink composition RICOH KK (JP) 2003-06-11 EP disclosed
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US disclosed
US-20020175982-A1 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2002-11-28 US disclosed
EP-1149877-A1 Decolorizable ink composition and ink jet printer using the ink composition Ricoh Company, Ltd. (JP) 2001-10-31 EP disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed