Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.76 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.76 |
| ▸ | NSD2 | O96028 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4963680 | 0.87 | KMT5B (0.80) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL12871473 | 0.85 | KMT5B (0.97) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL7206511 | 0.84 | KMT5B (0.84) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL7205699 | 0.84 | KMT5B (0.84) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL7205774 | 0.84 | KMT5B (0.84) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL7205707 | 0.84 | KMT5B (0.84) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL7207215 | 0.84 | KMT5B (0.89) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6872111 | 0.84 | KMT5B (0.89) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6872121 | 0.84 | KMT5B (0.89) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL7206080 | 0.81 | KMT5B (0.79) | KMT5BKMT5CNSD2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003070244-A1 | ANTAGONIST OF MELANIN CONCENTRATING HORMONE AND THEIR USES | ABBOTT LABORATORIES (US) | 2003-08-28 | — | — | WO | disclosed |