Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 4/20 | 0.52 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | TLK2 | Q86UE8 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366412 | 0.86 | MOGAT2 (0.55) | MOGAT2MGAT2PRKDCMAPTNTRK1 | |
| SCHEMBL5361507 | 0.86 | MOGAT2 (0.55) | MOGAT2MGAT2PRKDCMAPTNTRK1 | |
| SCHEMBL7131379 | 0.86 | MOGAT2 (0.57) | MOGAT2MGAT2PRKDCMAPTNTRK1 | |
| SCHEMBL5357745 | 0.84 | MOGAT2 (0.58) | MOGAT2MGAT2PRKDCPKMPKLR | |
| SCHEMBL7137732 | 0.84 | MOGAT2 (0.55) | MOGAT2MGAT2PRKDCNTRK1SYK | |
| SCHEMBL7136540 | 0.84 | MOGAT2 (0.54) | MOGAT2MGAT2PRKDCMAPTNTRK1 | |
| SCHEMBL5361728 | 0.84 | MOGAT2 (0.54) | MOGAT2MGAT2MAPTTLK2PDPK1 | |
| SCHEMBL5365561 | 0.83 | MOGAT2 (0.52) | MOGAT2MGAT2PRKDCPKMPKLR | |
| SCHEMBL7139520 | 0.83 | MOGAT2 (0.53) | MOGAT2MGAT2PRKDCMAPTNTRK1 | |
| SCHEMBL5368848 | 0.83 | MOGAT2 (0.53) | MOGAT2MGAT2PRKDCMAPTNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506763-B2 | Useful in prevention and treatment of protein kinase related disorders such as cancer | SUGEN, INC. | 2003-01-14 | — | — | US | disclosed |