SCHEMBL7134261

SCHEMBL7134261

CCCC(N)c1ccc(N)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.43
SLC6A4 P31645 1/20 0.41
TDP1 Q9NUW8 4/20 0.37
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 2/20 0.37
GFER P55789 2/20 0.37
PSMD14 O00487 1/20 0.37
MAPK1 P28482 1/20 0.37
RECQL P46063 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SLC6A3 Q01959 1/20 0.37
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ROCK1 Q13464 1/20 0.36
ACHE P22303 1/20 0.35
GAA P10253 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23222166 0.91 SLC2A1 (0.48) SLC2A1SLC6A4ALDH1A1MAPTROCK1
SCHEMBL9439909 0.87 SLC2A1 (0.53) SLC2A1SLC6A4TDP1TSHRALDH1A1
SCHEMBL19559157 0.86 SLC2A1 (0.43) SLC2A1SLC6A4ALDH1A1L3MBTL1ROCK1
SCHEMBL9439771 0.85 SLC2A1 (0.60) SLC2A1SLC6A4TSHRALDH1A1CYP3A4
SCHEMBL20697728 0.84 SLC2A1 (0.63) SLC2A1ALDH1A1CYP3A4MAPTCYP1A2
SCHEMBL9043076 0.84 SLC2A1 (0.63) SLC2A1ALDH1A1CYP3A4MAPTCYP1A2
SCHEMBL6542887 0.82 SLC2A1 (0.43) SLC2A1SLC6A4TDP1SLC6A3MAPT
SCHEMBL12056799 0.82 SLC2A1 (0.43) SLC2A1SLC6A4TDP1SLC6A3MAPT
SCHEMBL29172465 0.82 SLC2A1 (0.43) SLC2A1SLC6A4TDP1SLC6A3MAPT
SCHEMBL28572891 0.81 HRH1 (0.41) SLC2A1SLC6A4TDP1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10280181-B2 Coloring composition, anisotropic light absorption film, laminate, polarizing plate, image display device and compound FUJIFILM CORPORATION (JP) 2019-05-07 US disclosed
CN-1359390-B factor VIIa inhibitors AVENTIS PHARMA GMBH 2010-05-26 CN disclosed
EP-1189929-B1 FACTOR VIIA INHIBITORS AVENTIS PHARMA GMBH (DE) 2003-08-06 EP disclosed
US-6500803-B1 Factor VIIa inhibitors AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-12-31 US disclosed
CN-1359390-A factor VIIa inhibitors AVENTIS PHARMA GMBH (DE) 2002-07-17 CN disclosed
EP-1189929-A2 FACTOR VIIA INHIBITORS Aventis Pharma Deutschland GmbH (DE) 2002-03-27 EP disclosed
WO-2000075172-A2 FACTOR VIIa INHIBITORS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2000-12-14 WO disclosed
EP-1059302-A1 Factor VIIa inhibitors Aventis Pharma Deutschland GmbH (DE) 2000-12-13 EP disclosed
US-5336749-A Alicyclic diamines, alicyclic diisocyanates and polyisocyanato-isocyanurates and method for the preparation thereof MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-08-09 US disclosed
EP-0394058-B1 ALICYCLIC DIAMINES, ALICYCLIC DIISOCYANATES AND POLYISOCYANATO-ISOCYANURATES AND METHOD FOR THE PREPARATION THEREOF MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-25 EP disclosed
US-5210286-A Hydrogenation of corresponding aromatic compound, reaction with phosgene MITSUI TOATSU CHEMICALS, INC. (JP) 1993-05-11 US disclosed
US-5126426-A Catalytic hydrogenation of aromatic diamine MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-06-30 US disclosed
CN-1046522-A Alicyclic diamine and vulcabond of alicyclic ring and polyisocyanate root close isocyanuric acid ester and preparation method thereof MITSUI TOATSU CHEMICALS (JP) 1990-10-31 CN disclosed
EP-0394058-A1 Alicyclic diamines, alicyclic diisocyanates and polyisocyanato-isocyanurates and method for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-10-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10280181-B2 Coloring composition, anisotropic light absorption film, laminate, polarizing plate, image display device and compound AHR, CTNNA1, HTR1D SLC2A1 1500/4885SLC6A4 371/4885TDP1 3623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.