Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 7/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.40 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7137884 | 0.86 | HDAC6 (0.65) | KAT2BHDAC6TP53CYP3A4THRB | |
| SCHEMBL2344181 | 0.86 | HDAC6 (0.49) | KAT2BHDAC6TP53CYP3A4THRB | |
| SCHEMBL21841848 | 0.84 | HDAC6 (0.48) | KAT2BHDAC6TP53CYP3A4THRB | |
| SCHEMBL3634658 | 0.81 | TDP1 (0.45) | KAT2BHDAC6TP53CYP3A4THRB | |
| SCHEMBL8317776 | 0.81 | PTGER4 (0.51) | KAT2BHDAC6TP53CYP3A4THRB | |
| SCHEMBL5806008 | 0.81 | HDAC6 (0.63) | KAT2BHDAC6HTR1AADRA1DADRA1A | |
| SCHEMBL10126543 | 0.79 | KAT2B (0.54) | KAT2BHDAC6GUCY1A1GUCY1B1HTR1A | |
| SCHEMBL24185441 | 0.77 | HDAC6 (0.51) | HDAC6TP53CYP3A4THRBALOX15 | |
| SCHEMBL2611834 | 0.77 | KAT2B (0.52) | KAT2BHDAC6GUCY1A1GUCY1B1HTR1A | |
| SCHEMBL30527022 | 0.77 | HDAC6 (0.51) | HDAC6TP53CYP3A4THRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1321453-A2 | N-(Aminopropyl)-toluenediamines and their use as epoxy curing agents | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2003-06-25 | — | — | EP | claimed |
| US-6441238-B1 | USING N-AMINOPROPYLTOLUENEDIAMINE | AIR PRODUCTS AND CHEMICALS, INC. | 2002-08-27 | — | — | US | claimed |