Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2592311 | 0.87 | TSHR (0.62) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL30190646 | 0.85 | TSHR (0.66) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL31636169 | 0.85 | TSHR (0.66) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL277924 | 0.79 | TSHR (0.45) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28069197 | 0.79 | TSHR (0.45) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL6530911 | 0.78 | TSHR (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL9176522 | 0.78 | TSHR (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL9153653 | 0.78 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28446612 | 0.78 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL674235 | 0.78 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082624-B1 | OPTHALMIC LENS MADE OF ORGANIC GLASS, COMPRISING AN ANTI-SHOCK PRIMER COAT | ESSILOR INT (FR) | 2016-02-10 | — | — | EP | claimed |
| US-6503631-B1 | Organic glass, comprising, on at least one of its faces, an impact-resistant primer layer consisting of an aggregate of at least two-phase particles and in particular an aggregate of polymeric particles having a core/shell structure | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2003-01-07 | — | — | US | claimed |
| EP-0009690-B1 | USE OF POLYVINYLIDENE CHLORIDE IN THE PREPARATION OF POLYMERIC MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1982-10-27 | — | — | EP | claimed |