Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | TFEB | P19484 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7137704 | 1.00 | AR (0.46) | ARHPGDNR1H4MAOBNFE2L2 | |
| SCHEMBL7140107 | 0.91 | AR (0.46) | ARHPGDNR1H4MAOBNFE2L2 | |
| SCHEMBL7140111 | 0.91 | AR (0.46) | ARHPGDNR1H4MAOBNFE2L2 | |
| SCHEMBL7139094 | 0.78 | MAOB (0.42) | ARMAOBNFE2L2LMNATRPA1 | |
| SCHEMBL7139096 | 0.78 | MAOB (0.42) | ARMAOBNFE2L2LMNATRPA1 | |
| SCHEMBL7136724 | 0.78 | CAPN1 (0.47) | ARHPGDNFE2L2LMNARAB9A | |
| SCHEMBL7136726 | 0.78 | CAPN1 (0.47) | ARHPGDNFE2L2LMNARAB9A | |
| SCHEMBL7136707 | 0.77 | ABCB1 (0.49) | HPGDGAALMNAMAPTKDM4E | |
| SCHEMBL7144515 | 0.77 | KDM1A (0.44) | ARMAOBNFE2L2TFEBGAA | |
| SCHEMBL7144518 | 0.77 | KDM1A (0.44) | ARMAOBNFE2L2TFEBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996439-B1 | BETA-ALKOXYACRYLATES AGAINST MALARIA | HOFFMANN LA ROCHE (CH) | 2003-01-08 | — | — | EP | claimed |