Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 15/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139302 | 1.00 | SLC5A2 (0.46) | SLC5A2KDM1AKDM4EALDH1A1LMNA | |
| SCHEMBL4082091 | 1.00 | SLC5A2 (0.46) | SLC5A2KDM1AKDM4EALDH1A1LMNA | |
| SCHEMBL7137640 | 1.00 | SLC5A2 (0.46) | SLC5A2KDM1AKDM4EALDH1A1LMNA | |
| SCHEMBL7137636 | 1.00 | SLC5A2 (0.46) | SLC5A2KDM1AKDM4EALDH1A1LMNA | |
| SCHEMBL15270237 | 0.85 | SLC5A2 (0.67) | SLC5A2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL15298364 | 0.85 | SLC5A2 (0.67) | SLC5A2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL20220894 | 0.85 | SLC5A2 (0.67) | SLC5A2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL14590079 | 0.85 | SLC5A2 (0.67) | SLC5A2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL13245435 | 0.79 | SLC5A2 (0.47) | SLC5A2ALDH1A1LMNAHTR2AHTR2C | |
| SCHEMBL4382930 | 0.79 | SLC6A2 (0.37) | SLC5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509476-B1 | Leukotriene antagonists; antiallergens, antiinflammatory agents, and antiasthmatic agents | THE UNIVERSITY OF EAST ANGLIA (GB) | 2003-01-21 | — | — | US | disclosed |
| US-6160120-A | Process for preparing n-benzyl indoles | ELI LILLY AND COMPANY (US) | 2000-12-12 | — | — | US | disclosed |
| EP-0775694-A2 | Process for preparing N-benzyl indoles | University of East Anglia (GB) | 1997-05-28 | — | — | EP | disclosed |