Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.56 |
| ▸ | FNTB | P49356 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777591 | 1.00 | FNTA (0.56) | FNTAFNTBTDP1KMT2ATAS1R3 | |
| SCHEMBL6672029 | 0.92 | FNTA (0.54) | FNTAFNTBTDP1CHRNB2CHRNB4 | |
| SCHEMBL6672018 | 0.92 | FNTA (0.54) | FNTAFNTBTDP1CHRNB2CHRNB4 | |
| SCHEMBL6776535 | 0.87 | FNTA (0.53) | FNTAFNTBTDP1KMT2AMEN1 | |
| SCHEMBL6774486 | 0.85 | FNTA (0.57) | FNTAFNTBTDP1KMT2A | |
| SCHEMBL6774491 | 0.85 | FNTA (0.57) | FNTAFNTBTDP1KMT2A | |
| SCHEMBL6626106 | 0.85 | FNTA (0.65) | FNTAFNTBTDP1KMT2ATAS1R3 | |
| SCHEMBL6678981 | 0.83 | KMT2A (0.61) | FNTAFNTBTDP1KMT2ATAS1R3 | |
| SCHEMBL6672023 | 0.82 | NPC1 (0.44) | FNTAFNTBTDP1KMT2ACHRNB2 | |
| SCHEMBL6772100 | 0.81 | FNTA (0.56) | FNTAFNTBTDP1KMT2ATAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873123-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-0873123-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-02-03 | — | — | EP | disclosed |
| EP-0873123-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997017070-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-05-15 | — | — | WO | disclosed |