Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HMGCR | P04035 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140991 | 1.00 | RECQL (0.55) | RECQLTDP1PTPN7ALDH1A1KDM4E | |
| SCHEMBL7139900 | 1.00 | RECQL (0.55) | RECQLTDP1PTPN7ALDH1A1KDM4E | |
| SCHEMBL7139482 | 0.98 | PTPN7 (0.53) | RECQLTDP1PTPN7ALDH1A1KDM4E | |
| SCHEMBL17184097 | 0.93 | PTPN7 (0.50) | RECQLTDP1PTPN7ALDH1A1KDM4E | |
| SCHEMBL17184091 | 0.93 | PTPN7 (0.50) | RECQLTDP1PTPN7ALDH1A1KDM4E | |
| SCHEMBL27988146 | 0.93 | PTPN7 (0.50) | RECQLTDP1PTPN7ALDH1A1KDM4E | |
| SCHEMBL15756592 | 0.93 | PTPN7 (0.50) | RECQLTDP1PTPN7ALDH1A1KDM4E | |
| SCHEMBL17184087 | 0.93 | PTPN7 (0.50) | RECQLTDP1PTPN7ALDH1A1KDM4E | |
| SCHEMBL15756656 | 0.93 | PTPN7 (0.50) | RECQLTDP1PTPN7ALDH1A1KDM4E | |
| SCHEMBL17184110 | 0.93 | PTPN7 (0.50) | RECQLTDP1PTPN7ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6511670-B1 | Compounds with shorter alkyl chains such as 3,8-dithia-5-docosynoic acid; treating acne and inflammation disorders; peroxisome proliferator activated receptor activators | SOCIETE L'OREAL S.A. (FR) | 2003-01-28 | — | — | US | disclosed |
| US-5310959-A | Reacting 1-decyne with 1,4-dihalo-2-butyne using a strong base and then reacting with 5-hexynoic acid; reacting with an amine in the presense of carbonyldiimidazole to amidate | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1994-05-10 | — | — | US | disclosed |
| US-5268494-A | Compound containing conjugated triple bonds | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1993-12-07 | — | — | US | disclosed |
| US-5151534-A | Antiallergens, antiinflammatory agents or skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1992-09-29 | — | — | US | disclosed |
| US-5066427-A | Skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES DITE CIRD (FR) | 1991-11-19 | — | — | US | disclosed |
| US-4877789-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES DITE C.I.R.D. (FR) | 1989-10-31 | — | — | US | disclosed |