Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 19/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749251 | 0.87 | ICAM1 (0.59) | ICAM1KDM4EGAAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL6752007 | 0.86 | ICAM1 (0.58) | ICAM1KDM4EGAAMAPTHPGD | |
| SCHEMBL6747234 | 0.83 | ICAM1 (0.63) | ICAM1VCAM1 | |
| SCHEMBL6745225 | 0.83 | ICAM1 (0.63) | ICAM1KDM4EGAAMAPTHPGD | |
| SCHEMBL6749084 | 0.82 | ICAM1 (0.66) | ICAM1KDM4EGAAMAPTHPGD | |
| SCHEMBL6745780 | 0.82 | ICAM1 (0.59) | ICAM1KDM4EGAAMAPTHPGD | |
| SCHEMBL6747638 | 0.82 | ICAM1 (0.63) | ICAM1VCAM1 | |
| SCHEMBL6745506 | 0.81 | ICAM1 (0.60) | ICAM1KDM4EGAAMAPTHPGD | |
| SCHEMBL6745660 | 0.80 | ICAM1 (0.66) | ICAM1KDM4EGAAMAPTHPGD | |
| SCHEMBL6745784 | 0.80 | ICAM1 (0.66) | ICAM1KDM4EGAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |