Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 18/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.67 |
| ▸ | PDE4A | P27815 | 14/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.67 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141179 | 0.91 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL7140292 | 0.90 | PDE4D (0.64) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL7143191 | 0.85 | PDE4B (0.61) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL7133913 | 0.84 | PDE4D (0.59) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL7362470 | 0.82 | PDE4D (0.76) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL7361858 | 0.82 | PDE4D (0.76) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL7354074 | 0.82 | PDE4D (0.76) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL7354173 | 0.82 | PDE4D (0.83) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL7355711 | 0.82 | PDE4D (0.71) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL15270505 | 0.82 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4CCYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086096-B1 | BENZAMIDES WITH TETRAHYDROFURANYLOXY SUBSTITUTENTS AS PHOSPHODIESTERASE 4 INHIBITORS | ALTANA PHARMA AG (DE) | 2003-07-23 | — | — | EP | disclosed |
| US-6303789-B1 | TREATING AIRWAY DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2001-10-16 | — | — | US | disclosed |