Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.48 |
| ▸ | F7 | P08709 | 7/20 | 0.48 |
| ▸ | F10 | P00742 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 3/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145086 | 0.90 | F2 (0.59) | F2PRSS1F7F10F3 | |
| Acetic Acid SCHEMBL8120257 | 0.89 | F2 (0.58) | F2PRSS1F7F10F3 | |
| SCHEMBL5883495 | 0.86 | F10 (0.42) | F2PRSS1F7F10SMN1; SMN2 | |
| SCHEMBL8120592 | 0.84 | F7 (0.42) | F2PRSS1F7F10KMT2A | |
| SCHEMBL7150630 | 0.82 | F2 (0.55) | F2PRSS1F7F10KMT2A | |
| SCHEMBL8120265 | 0.82 | F2 (0.55) | F2PRSS1F7F10F3 | |
| SCHEMBL7148118 | 0.80 | F2 (0.51) | F2PRSS1F7F10ALDH1A1 | |
| SCHEMBL8127685 | 0.76 | F2 (0.54) | F2PRSS1F7F10SMN1; SMN2 | |
| SCHEMBL8122404 | 0.75 | F2 (0.54) | F2PRSS1F7F10SMN1; SMN2 | |
| SCHEMBL7148516 | 0.75 | F7 (0.61) | F2PRSS1F7F10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921116-B1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | EP | disclosed |
| US-6140353-A | USED AS MEDICAMENTS FOR THE TREATMENT AND/OR PREVENTION OF THROMBOSES, APOPLEXY, CARDIAC INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS OR AS ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |