Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18952376 | 0.79 | NR1H4 (0.43) | POLBKDM4EALDH1A1ACLYSMN1; SMN2 | |
| SCHEMBL9511883 | 0.76 | POLB (0.56) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13073786 | 0.72 | POLB (0.56) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4565884 | 0.71 | HDAC3 (0.57) | POLBKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL28859305 | 0.71 | POLB (0.50) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL950942 | 0.71 | POLB (0.62) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL165558 | 0.70 | POLB (0.61) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9958891 | 0.70 | POLB (0.60) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28278344 | 0.70 | CA12 (0.49) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10986752 | 0.69 | HDAC3 (0.58) | POLBKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369248-B1 | HYDROXY ESTERS FOR PERFUMES | GIVAUDAN SA (CH) | 2002-04-09 | — | — | US | claimed |
| EP-0989970-A1 | FRAGRANCE PRECURSOR COMPOUNDS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2000-04-05 | — | — | EP | claimed |
| EP-0980863-A1 | Oxime carboxylic acid derivatives | Givaudan Roure (International) S.A. (CH) | 2000-02-23 | — | — | EP | claimed |
| WO-1998058899-A1 | FRAGRANCE PRECURSOR COMPOUNDS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1998-12-30 | — | — | WO | claimed |
| US-6521797-B1 | Precursors for organoleptic compounds, especially for flavors, fragrances and masking agents, and/or antimicrobial compounds; 2,6-dimethyl-oct-5-enal generated by the cleavage of the oxime derivative | GIVAUDAN AG (CH) | 2003-02-18 | — | — | US | disclosed |
| US-6369248-B1 | HYDROXY ESTERS FOR PERFUMES | GIVAUDAN SA (CH) | 2002-04-09 | — | — | US | disclosed |
| US-6258854-B1 | KETONE ETHERS FOR ODORS | GIVAUDAN ROURE ( INTERNATIONAL ) SA (CH) | 2001-07-10 | — | — | US | disclosed |
| EP-0989970-A1 | FRAGRANCE PRECURSOR COMPOUNDS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2000-04-05 | — | — | EP | disclosed |
| EP-0983990-A2 | Ketones useful as precursors for organoleptic compounds | Givaudan Roure (International) S.A. (CH) | 2000-03-08 | — | — | EP | disclosed |
| EP-0980863-A1 | Oxime carboxylic acid derivatives | Givaudan Roure (International) S.A. (CH) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998058899-A1 | FRAGRANCE PRECURSOR COMPOUNDS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1998-12-30 | — | — | WO | disclosed |