SCHEMBL7141084

SCHEMBL7141084

COc1cc(C(=O)NC(=O)C2CCN(c3ccncc3)CC2)cc(OCCc2ccc(Cl)cc2Cl)c1Cl

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7652161 0.89 F10 (0.77) F10
SCHEMBL6066535 0.88 F10 (1.00) F10
SCHEMBL6066427 0.81 F10 (1.00) F10
SCHEMBL6066474 0.81 F10 (1.00) F10
SCHEMBL6066486 0.80 F10 (1.00) F10
SCHEMBL6066484 0.80 F10 (1.00) F10
SCHEMBL7646337 0.79 F10 (0.76) F10
SCHEMBL6067053 0.78 F10 (1.00) F10
SCHEMBL6066450 0.77 F10 (0.78) F10
SCHEMBL6066446 0.77 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1349847-A1 OXYBENZAMIDES DERIVATIVES AS FACTOR XA INHIBITORS Aventis Pharma Deutschland GmbH (DE) 2003-10-08 EP disclosed
WO-2002051831-A1 OXYBENZAMIDES DERIVATIVES AS FACTOR XA INHIBITORS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-07-04 WO disclosed