SCHEMBL7141965

SCHEMBL7141965

CCO[Si](C)(CCCOCC1CO1)OCC.[SiH4]

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.58
TSHR P16473 2/20 0.55
ALDH1A1 P00352 4/20 0.54
TDP1 Q9NUW8 1/20 0.54
MAPK1 P28482 1/20 0.38
PDK1 Q15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43462 0.98 SMN1; SMN2 (0.59) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL620110 0.98 SMN1; SMN2 (0.59) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL10876878 0.98 SMN1; SMN2 (0.59) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL29264166 0.95 SMN1; SMN2 (0.56) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL28753399 0.95 SMN1; SMN2 (0.56) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
Alcohol SCHEMBL28921752 0.94 SMN1; SMN2 (0.54) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL28372728 0.94 SMN1; SMN2 (0.54) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL5605637 0.93 TSHR (0.60) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL5081669 0.92 SMN1; SMN2 (0.53) SMN1; SMN2TSHRALDH1A1TDP1MAPK1
SCHEMBL3792866 0.92 SMN1; SMN2 (0.57) SMN1; SMN2TSHRALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103167905-A Process for improving the storage stability of aqueous composite particle dispersions BASF SE 2013-06-19 CN disclosed
EP-1289677-A4 WATER-BASED PRIMER FOR PROMOTING ADHESION OF POLYURETHANE-BASED SEALANTS AND ADHESIVES SIKA CORP (US) 2003-11-05 EP disclosed
EP-1289677-A1 WATER-BASED PRIMER FOR PROMOTING ADHESION OF POLYURETHANE-BASED SEALANTS AND ADHESIVES Sika Corporation (US) 2003-03-12 EP disclosed
US-6511752-B1 Using such as isopropyltri(n-ethylenediamino)ethyltitanate and 3-glycidoxypropyltrimethoxysilane which react with both polymer and float glass or ceramic frit substrate; storage stability; little or no volatile organic emissions SIKA CORPORATION 2003-01-28 US disclosed
WO-2001091923-A1 WATER-BASED PRIMER FOR PROMOTING ADHESION OF POLYURETHANE-BASED SEALANTS AND ADHESIVES SIKA CORPORATION (US) 2001-12-06 WO disclosed