Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139748 | 0.92 | ESR1 (0.55) | ESR2ESR1 | |
| SCHEMBL7141350 | 0.92 | ESR1 (0.57) | ESR2ESR1 | |
| SCHEMBL7146404 | 0.89 | ESR1 (0.55) | ESR2ESR1 | |
| SCHEMBL7143964 | 0.88 | ESR1 (0.57) | ESR2ESR1 | |
| SCHEMBL7140944 | 0.86 | ESR1 (0.56) | ESR2ESR1 | |
| SCHEMBL7163311 | 0.86 | EBP (0.58) | ESR2ESR1 | |
| SCHEMBL7139824 | 0.85 | ESR1 (0.56) | ESR2ESR1 | |
| SCHEMBL7141345 | 0.85 | EBP (0.57) | ESR2ESR1 | |
| SCHEMBL7136715 | 0.81 | ESR1 (0.55) | ESR2ESR1 | |
| SCHEMBL7144833 | 0.80 | ESR1 (0.54) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832880-B1 | Dihydrobenzofluorene compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-0832880-A1 | Dihydrobenzofluorene compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |