Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 18/20 | 1.00 |
| ▸ | PDE4A | P27815 | 17/20 | 1.00 |
| ▸ | PDE4C | Q08493 | 17/20 | 1.00 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.73 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.73 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142481 | 1.00 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL7142475 | 1.00 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL7142625 | 0.99 | PDE4B (0.98) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL7142619 | 0.99 | PDE4B (0.98) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL7142621 | 0.99 | PDE4B (0.98) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL7140035 | 0.93 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL7140032 | 0.93 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL7140029 | 0.93 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL7146693 | 0.93 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CPDE7A | |
| SCHEMBL7146692 | 0.93 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971901-B1 | PHTHALAZINONES | ALTANA PHARMA AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| US-6103718-A | Phthalazinones | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-08-15 | — | — | US | disclosed |
| EP-0971901-A1 | PHTHALAZINONES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2000-01-19 | — | — | EP | disclosed |
| WO-1999031071-A1 | NEW PHTHALAZINONES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |
| WO-1998031674-A1 | PHTHALAZINONES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-07-23 | — | — | WO | disclosed |