Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 7/20 | 0.56 |
| ▸ | F2 | P00734 | 6/20 | 0.56 |
| ▸ | F10 | P00742 | 6/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 3/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142658 | 1.00 | F7 (0.56) | F7F2F10PRSS1SLC1A3 | |
| SCHEMBL7142671 | 1.00 | F7 (0.56) | F7F2F10PRSS1SLC1A3 | |
| SCHEMBL7147565 | 0.88 | F7 (0.54) | F7F2F10PRSS1SLC1A3 | |
| SCHEMBL7147574 | 0.88 | F7 (0.54) | F7F2F10PRSS1SLC1A3 | |
| SCHEMBL7147569 | 0.88 | F7 (0.54) | F7F2F10PRSS1SLC1A3 | |
| SCHEMBL7142565 | 0.88 | F7 (0.73) | F7F2F10PRSS1SLC1A3 | |
| SCHEMBL7142569 | 0.88 | F7 (0.73) | F7F2F10PRSS1SLC1A3 | |
| SCHEMBL7142570 | 0.88 | F7 (0.73) | F7F2F10PRSS1SLC1A3 | |
| SCHEMBL7147647 | 0.87 | F7 (0.62) | F7F2F10PRSS1SLC1A3 | |
| SCHEMBL7147651 | 0.87 | F7 (0.62) | F7F2F10PRSS1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921116-B1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | EP | disclosed |
| US-6140353-A | USED AS MEDICAMENTS FOR THE TREATMENT AND/OR PREVENTION OF THROMBOSES, APOPLEXY, CARDIAC INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS OR AS ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |