SCHEMBL7143320

SCHEMBL7143320

CC(=O)C(C)C1CCCCCCCCCCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 9/20 0.44
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
MMP2 P08253 2/20 0.42
CA9 Q16790 2/20 0.42
ATM Q13315 1/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP3A4 P08684 1/20 0.37
EPHX2 P34913 1/20 0.37
SHBG P04278 1/20 0.37
DHODH Q02127 1/20 0.37
DPP4 P27487 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12913433 1.00 EPHX1 (0.44) EPHX1CA12CA1CA2MMP2
SCHEMBL11606325 1.00 EPHX1 (0.44) EPHX1CA12CA1CA2MMP2
SCHEMBL15325041 0.92
SCHEMBL6242702 0.87 EPHX1 (0.46) EPHX1CA12CA1CA2MMP2
SCHEMBL27713854 0.84 EPHX1 (0.42) EPHX1CA12CA1CA2MMP2
SCHEMBL29295753 0.81 KDM4E (0.41) SMN1; SMN2ALDH1A1KDM4E
SCHEMBL1188709 0.80 EPHX1 (0.44) EPHX1CA12CA1CA2MMP2
SCHEMBL2055541 0.80 EPHX1 (0.44) EPHX1CA12CA1CA2MMP2
Cyclohexane SCHEMBL18344237 0.80 EPHX1 (0.44) EPHX1CA12CA1CA2MMP2
SCHEMBL1595664 0.80 EPHX1 (0.44) EPHX1CA12CA1CA2MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1027317-B1 REACTION OF ALKENES WITH EPOXIDES, THE PRODUCTS THEREOF AND THEIR USE AS FRAGRANCE COMPOUNDS QUEST INT (NL) 2003-04-02 EP disclosed
US-6444637-B1 FORMING ALDEHYDE BY LEWIS ACID-CATALYZED REACTION OF ALKENE WITH EPOXIDE QUEST INTERNATIONAL B.V. (NL) 2002-09-03 US disclosed
EP-1027317-A1 REACTION OF ALKENES WITH EPOXIDES, THE PRODUCTS THEREOF AND THEIR USE AS FRAGRANCE COMPOUNDS QUEST INTERNATIONAL B.V. (NL) 2000-08-16 EP disclosed
EP-0926121-A1 Reaction of alkenes with epoxides, the products thereof and their use as fragrance compounds QUEST INTERNATIONAL B.V. (NL) 1999-06-30 EP disclosed
WO-1999021817-A1 REACTION OF ALKENES WITH EPOXIDES, THE PRODUCTS THEREOF AND THEIR USE AS FRAGRANCE COMPOUNDS QUEST INTERNATIONAL B.V. (NL) 1999-05-06 WO disclosed