Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 20/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.69 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5526434 | 0.93 | PDE7A (0.79) | PDE7APDE4DPDE7B | |
| SCHEMBL4252297 | 0.93 | PDE7A (0.79) | PDE7APDE4DPDE7B | |
| SCHEMBL4250457 | 0.93 | PDE7A (0.79) | PDE7APDE4DPDE7B | |
| SCHEMBL4250459 | 0.93 | PDE7A (0.79) | PDE7APDE4DPDE7B | |
| SCHEMBL7146139 | 0.89 | PDE7A (0.71) | PDE7APDE4DPDE7B | |
| SCHEMBL4255859 | 0.82 | PDE7A (1.00) | PDE7APDE4DPDE7B | |
| SCHEMBL5527240 | 0.82 | PDE7A (1.00) | PDE7APDE4DPDE7B | |
| SCHEMBL4255856 | 0.82 | PDE7A (1.00) | PDE7APDE4DPDE7B | |
| SCHEMBL4256540 | 0.81 | PDE7A (0.82) | PDE7APDE4DPDE7B | |
| SCHEMBL4256545 | 0.81 | PDE7A (0.82) | PDE7APDE4DPDE7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326853-A1 | NEW THIADIAZOLES AND OXADIAZOLES AND THEIR USE AS PHOSPHODIESTERASE-7 INHIBITORS | Warner-Lambert Company LLC (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028847-A1 | NEW THIADIAZOLES AND OXADIAZOLES AND THEIR USE AS PHOSPHODIESTERASE-7 INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-04-11 | — | — | WO | disclosed |