Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7143454 | 0.75 | NPSR1 (0.42) | NPSR1ALDH1A1HTTPDK1PDK2 | |
| SCHEMBL7143446 | 0.73 | NPSR1 (0.46) | NPSR1ALDH1A1HTTPDK1PDK2 | |
| SCHEMBL3547267 | 0.72 | NPSR1 (0.42) | NPSR1ALDH1A1HTTPDK1PDK2 | |
| SCHEMBL8331183 | 0.71 | NPSR1 (0.60) | NPSR1ALDH1A1HTTPDK1PDK2 | |
| SCHEMBL2956140 | 0.71 | NPSR1 (0.60) | NPSR1ALDH1A1HTTPDK1PDK2 | |
| SCHEMBL13548747 | 0.71 | NPSR1 (0.43) | NPSR1ALDH1A1HTTPDK1PDK2 | |
| SCHEMBL3547269 | 0.69 | NPSR1 (0.42) | NPSR1ALDH1A1HTTPDK1PDK2 | |
| SCHEMBL7528689 | 0.69 | NPSR1 (0.57) | NPSR1ALDH1A1HTTPDK1PDK2 | |
| SCHEMBL27651146 | 0.68 | NPSR1 (0.56) | NPSR1ALDH1A1HTTKMT2APOLB | |
| SCHEMBL9336413 | 0.68 | NPSR1 (0.59) | NPSR1ALDH1A1HTTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341757-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | Syngenta Participations AG (CH) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002038542-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-05-16 | — | — | WO | disclosed |