Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.50 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.50 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472939 | 0.93 | SLC2A1 (0.44) | SLC2A1 | |
| SCHEMBL7214694 | 0.87 | — | — | |
| SCHEMBL8455189 | 0.82 | — | — | |
| SCHEMBL178925 | 0.82 | BCHE (0.51) | BCHETRPC3TRPC4TRPC5 | |
| SCHEMBL8215131 | 0.80 | SLC2A1 (0.55) | BCHETRPC3TRPC4TRPC5SLC2A1 | |
| Hydrochloric Acid SCHEMBL8211807 | 0.69 | POLB (0.51) | — | |
| SCHEMBL22619945 | 0.69 | BCHE (1.00) | BCHETRPC3TRPC4TRPC5 | |
| SCHEMBL10069522 | 0.69 | SLC2A1 (0.66) | BCHETRPC3TRPC4TRPC5SLC2A1 | |
| SCHEMBL178883 | 0.69 | BCHE (0.56) | BCHETRPC3TRPC4TRPC5SLC2A1 | |
| Hydrochloric Acid SCHEMBL23295188 | 0.68 | BCHE (0.97) | BCHETRPC3TRPC4TRPC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003500395-A | — | — | 2003-01-07 | — | — | JP | claimed |
| WO-2000071522-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS METHIONYL T-RNA SYNTHETASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-30 | — | — | WO | claimed |
| WO-2000071522-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS METHIONYL T-RNA SYNTHETASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-30 | — | — | WO | disclosed |