SCHEMBL7144412

SCHEMBL7144412

FNS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL929348 0.61
SCHEMBL372757 0.61
Iodide SCHEMBL9818601 0.55
SCHEMBL1846678 0.55
SCHEMBL23296276 0.50
SCHEMBL5421246 0.50
SCHEMBL11265892 0.50
SCHEMBL13447783 0.50
SCHEMBL7737619 0.50
SCHEMBL5869492 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054859-A4 PROCESSES AND INTERMEDIATES USEFUL TO MAKE ANTIFOLATES LILLY CO ELI (US) 2003-03-05 EP claimed
EP-1054859-A1 PROCESSES AND INTERMEDIATES USEFUL TO MAKE ANTIFOLATES ELI LILLY AND COMPANY (US) 2000-11-29 EP claimed
WO-1999041230-A1 PROCESSES AND INTERMEDIATES USEFUL TO MAKE ANTIFOLATES ELI LILLY AND COMPANY (US) 1999-08-19 WO claimed
US-20150336926-A1 FLUORINATION OF ARYL COMPOUNDS NIH 2015-11-26 US disclosed
WO-2014107379-A1 FLUORINATION OF ARYL COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-07-10 WO disclosed
EP-1558607-B1 COMPOSITIONS USEFUL AS INHIBITORS OF ROCK AND OTHER PROTEIN KINASES VERTEX PHARMA (US) 2010-05-05 EP disclosed
US-20080247682-A1 STAND-UP FLEXIBLE POUCH AND METHOD OF FORMING POUCH PAC INNOVATIONS, LLC (US) 2008-10-09 US disclosed