⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844526 | 0.64 | — | — | |
| SCHEMBL12808170 | 0.64 | — | — | |
| SCHEMBL14303643 | 0.64 | — | — | |
| SCHEMBL2744703 | 0.64 | — | — | |
| SCHEMBL12446829 | 0.64 | — | — | |
| SCHEMBL13213163 | 0.64 | — | — | |
| SCHEMBL12209468 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL29217216 | 0.61 | — | — | |
| SCHEMBL18120037 | 0.57 | — | — | |
| SCHEMBL282939 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3586838-B1 | AMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| CN-101076519-A | Amide compound and thrombopoietin receptor activator | NISSAN CHEMICAL IND LTD (JP) | 2007-11-21 | — | — | CN | disclosed |
| US-6617456-B1 | Aminoalkoxy- or hydroxyalkoxy- camptothecin compound that can be bound to a polysaccharide having carboxyl groups via an amino acid or a peptide group; antitumor agents | TANABE SEIYAKU CO., LTD. (JP) | 2003-09-09 | — | — | US | disclosed |
| US-6512118-B1 | Pharmaceutically acceptable salt thereof show excellent antitumor activities against various tumors, especially they show excellent therapeutic effects on solid tumors such as pulmonary cancer, uterine cancer, ovarian cancer, breast | TANABE SEIYAKU CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |
| EP-0781781-B1 | Camptothecin derivatives | TANABE SEIYAKU CO (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-5892043-A | MIXTURE WITH POLYSACCHARIDE AND PEPTIDE; ANTITUMOR AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0781781-A2 | Camptothecin derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |