⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL792711 | 0.75 | — | — | |
| SCHEMBL10827535 | 0.75 | — | — | |
| SCHEMBL2182690 | 0.75 | — | — | |
| SCHEMBL9935558 | 0.73 | — | — | |
| SCHEMBL10500132 | 0.73 | — | — | |
| Zinc Ion SCHEMBL30275673 | 0.73 | TSHR (0.36) | — | |
| SCHEMBL1269698 | 0.73 | — | — | |
| SCHEMBL9516696 | 0.73 | — | — | |
| SCHEMBL4829066 | 0.73 | — | — | |
| SCHEMBL29289425 | 0.73 | TP53 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100404505-C | Novel substituted indoles | ASTRAZENECA AB (SE) | 2008-07-23 | — | — | CN | disclosed |
| CN-1671659-A | Novel substituted indoles | ASTRAZENECA AB (SE) | 2005-09-21 | — | — | CN | disclosed |
| EP-1235536-B1 | MEDICAL DEVICE comprising a synthetic surface having nucleic acid for in vivo induction of its endothelialisation | XENERATE AB (SE) | 2003-06-25 | — | — | EP | disclosed |
| US-20030059463-A1 | Medical device | FIT BIOTECH OY PLC (FI) | 2003-03-27 | — | — | US | disclosed |
| EP-1235536-A1 | MEDICAL DEVICE | Lahtinen, Mika (SE) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001041674-A1 | MEDICAL DEVICE | LAHTINEN MIKA (SE) | 2001-06-14 | — | — | WO | disclosed |
| WO-1996003980-A1 | IMPROVED EFFERVESCENT DELIVERY SYSTEM | BAYER CORPORATION (US) | 1996-02-15 | — | — | WO | disclosed |