Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102326 | 1.00 | ADORA2A (0.57) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7103626 | 0.91 | ADORA2A (0.47) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7152909 | 0.88 | ADORA2A (0.57) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7105571 | 0.88 | ADORA2A (0.57) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7103947 | 0.86 | ADORA2A (0.57) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL6839238 | 0.86 | ADORA2A (0.56) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7601344 | 0.86 | ADORA2A (0.56) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7601339 | 0.86 | ADORA2A (0.56) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7151757 | 0.86 | ADORA2A (0.57) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7526585 | 0.84 | ADORA2A (0.65) | ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090023-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-09-10 | — | — | EP | claimed |