Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.35 |
| ▸ | HMGCR | P04035 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472202 | 0.90 | PTPN7 (0.41) | TSHRTDP1PTPN7HMGCRRECQL | |
| SCHEMBL3032195 | 0.90 | PTPN7 (0.41) | TSHRTDP1PTPN7HMGCRRECQL | |
| SCHEMBL11475049 | 0.90 | PTPN7 (0.41) | TSHRTDP1PTPN7HMGCRRECQL | |
| SCHEMBL10972886 | 0.86 | PTPN7 (0.41) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL3015199 | 0.84 | TSHR (0.35) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL3032193 | 0.81 | PTPN7 (0.35) | TSHRTDP1PTPN7HMGCRRECQL | |
| SCHEMBL8413427 | 0.80 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL21484045 | 0.80 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL28214293 | 0.80 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL8412547 | 0.80 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280813-A1 | ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES | University College Cardiff Consultants Limited (GB) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001085749-A1 | ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-11-15 | — | — | WO | disclosed |