SCHEMBL7144935

SCHEMBL7144935

CCCCCCCCCCCCCCCC(=O)O[C@]1(C(=O)CO)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 8/20 1.00
HIF1A Q16665 7/20 0.95
KMT2A Q03164 3/20 0.95
PGR P06401 4/20 0.88
NR3C1 P04150 4/20 0.88
SMN1; SMN2 Q16637 4/20 0.70
MAPT P10636 3/20 0.70
POLB P06746 1/20 0.70
GAA P10253 1/20 0.70
AR P10275 2/20 0.68
CHRM1 P11229 1/20 0.68
CYP3A4 P08684 2/20 0.64
HPGD P15428 1/20 0.64
MEN1 O00255 1/20 0.64
MLNR O43193 1/20 0.64
NR1I2 O75469 1/20 0.64
LMNA P02545 1/20 0.64
ADORA3 P0DMS8 1/20 0.64
HTT P42858 1/20 0.64
SLC6A3 Q01959 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20668513 1.00 NR3C2 (1.00) NR3C2HIF1AKMT2APGRNR3C1
SCHEMBL7142707 1.00 NR3C2 (1.00) NR3C2HIF1AKMT2APGRNR3C1
SCHEMBL4886133 1.00 NR3C2 (1.00) NR3C2HIF1AKMT2APGRNR3C1
SCHEMBL7137194 1.00 NR3C2 (1.00) NR3C2HIF1AKMT2APGRNR3C1
SCHEMBL28378823 1.00 NR3C2 (1.00) NR3C2HIF1AKMT2APGRNR3C1
SCHEMBL14936016 1.00 NR3C2 (1.00) NR3C2HIF1AKMT2APGRNR3C1
SCHEMBL14935780 1.00 NR3C2 (1.00) NR3C2HIF1AKMT2APGRNR3C1
SCHEMBL14935882 1.00 NR3C2 (1.00) NR3C2HIF1AKMT2APGRNR3C1
SCHEMBL14965094 0.99 NR3C2 (0.98) NR3C2HIF1AKMT2APGRNR3C1
SCHEMBL5084676 0.99 NR3C2 (1.00) NR3C2HIF1AKMT2APGRNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0041772-B2 FAT EMULSION CONTAINING A STEROID GREEN CROSS CORPORATION (JP) 1990-04-18 EP claimed
EP-0041772-B1 FAT EMULSION CONTAINING A STEROID GREEN CROSS CORPORATION (JP) 1984-10-17 EP claimed
US-4340594-A Fat emulsion containing steroid THE GREEN CROSS CORPORATION (JP) 1982-07-20 US claimed
EP-0041772-A2 Fat emulsion containing a steroid GREEN CROSS CORPORATION (JP) 1981-12-16 EP claimed
EP-0331755-B2 MEDICINE-CONTAINING FAT EMULSION OF THE TYPE PREPARED IMMEDIATELY BEFORE USE AND PROCESS FOR PREPARING MEDICINE-CONTAINING FAT EMULSION TEIJIN LTD (JP) 2003-02-05 EP disclosed
EP-0556394-B1 LYOPHILIZED PREPARATION AND PRODUCTION THEREOF NIPPON SHINYAKU CO LTD (JP) 2002-06-19 EP disclosed
US-5651991-A FATTY EMULSION OF NON-LIPOSOME PARTICLES CONTAINING DRUG IN CORE, AND HAVING LIPID SURFACE LAYER NIPPON SHINYAKU CO. LTD. (JP) 1997-07-29 US disclosed
US-5635491-A Lyophilized fatty emulsions and a process for the production thereof NIPPON SHINYAKU CO., LTD. (JP) 1997-06-03 US disclosed
EP-0315079-B1 Drug carriers NIPPON SHINYAKU CO LTD (JP) 1995-03-01 EP disclosed
EP-0556394-A1 LYOPHILIZED PREPARATION AND PRODUCTION THEREOF NIPPON SHINYAKU COMPANY, LIMITED (JP) 1993-08-25 EP disclosed
EP-0331755-B1 MEDICINE-CONTAINING FAT EMULSION OF THE TYPE PREPARED IMMEDIATELY BEFORE USE AND PROCESS FOR PREPARING MEDICINE-CONTAINING FAT EMULSION TEIJIN LIMITED (JP) 1993-08-11 EP disclosed
US-5229422-A Drug delivery TEIJIN LIMITED (JP) 1993-07-20 US disclosed
US-4693999-A ANTIINFLAMMATORY, ANTIALLERGEN AGENTS AKTIEBOLAGET DRACO (SE) 1987-09-15 US disclosed
CN-85105713-A The preparation method who contains the liposome of steroide steroid ester 1987-01-28 CN disclosed
EP-0170642-A2 Liposomes containing steroid esters Aktiebolaget Draco (SE) 1986-02-05 EP disclosed
EP-0041772-B1 FAT EMULSION CONTAINING A STEROID GREEN CROSS CORPORATION (JP) 1984-10-17 EP disclosed
US-4347234-A Medicinally useful, shaped mass of collagen resorbable in the body MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-08-31 US disclosed
US-4340594-A Fat emulsion containing steroid THE GREEN CROSS CORPORATION (JP) 1982-07-20 US disclosed
EP-0041772-A2 Fat emulsion containing a steroid GREEN CROSS CORPORATION (JP) 1981-12-16 EP disclosed
US-4291013-A Medicinally useful, shaped mass of collagen resorbable in the body MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1981-09-22 US disclosed