Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.42 |
| ▸ | F7 | P08709 | 4/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144961 | 1.00 | ADRB3 (0.43) | ADRB3SLC1A3SLC1A2RAB9AF2 | |
| SCHEMBL7140854 | 0.90 | F7 (0.43) | SLC1A3SLC1A2RAB9AF2PRSS1 | |
| SCHEMBL7140860 | 0.90 | F7 (0.43) | SLC1A3SLC1A2RAB9AF2PRSS1 | |
| SCHEMBL7142631 | 0.87 | F2 (0.49) | SLC1A3SLC1A2RAB9AF2PRSS1 | |
| SCHEMBL7142637 | 0.87 | F2 (0.49) | SLC1A3SLC1A2RAB9AF2PRSS1 | |
| SCHEMBL7150831 | 0.86 | AKR1B1 (0.46) | SLC1A3SLC1A2RAB9AF2PRSS1 | |
| SCHEMBL7147310 | 0.86 | HPGD (0.43) | SLC1A3SLC1A2RAB9AF2PRSS1 | |
| SCHEMBL7147306 | 0.86 | HPGD (0.43) | SLC1A3SLC1A2RAB9AF2PRSS1 | |
| SCHEMBL7146079 | 0.84 | F7 (0.43) | SLC1A3SLC1A2RAB9AF2PRSS1 | |
| SCHEMBL7146093 | 0.84 | F7 (0.43) | SLC1A3SLC1A2RAB9AF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921116-B1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | EP | disclosed |
| US-6140353-A | USED AS MEDICAMENTS FOR THE TREATMENT AND/OR PREVENTION OF THROMBOSES, APOPLEXY, CARDIAC INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS OR AS ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |