Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 20/20 | 0.83 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.83 |
| ▸ | PDE4A | P27815 | 10/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.69 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.69 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145709 | 1.00 | PDE4D (0.83) | PDE4DSLC6A2PDE4APDE4BPDE4C | |
| SCHEMBL7140290 | 1.00 | PDE4D (0.83) | PDE4DSLC6A2PDE4APDE4BPDE4C | |
| SCHEMBL7140287 | 1.00 | PDE4D (0.83) | PDE4DSLC6A2PDE4APDE4BPDE4C | |
| SCHEMBL7140285 | 1.00 | PDE4D (0.83) | PDE4DSLC6A2PDE4APDE4BPDE4C | |
| SCHEMBL7145712 | 1.00 | PDE4D (0.83) | PDE4DSLC6A2PDE4APDE4BPDE4C | |
| SCHEMBL6478214 | 0.91 | PDE4D (0.81) | PDE4DSLC6A2PDE4APDE4BPDE4C | |
| SCHEMBL6477606 | 0.91 | PDE4D (1.00) | PDE4DSLC6A2PDE4APDE4BPDE4C | |
| SCHEMBL6478487 | 0.91 | PDE4D (0.81) | PDE4DSLC6A2PDE4APDE4BPDE4C | |
| SCHEMBL6478491 | 0.91 | PDE4D (0.81) | PDE4DSLC6A2PDE4APDE4BPDE4C | |
| SCHEMBL2693531 | 0.91 | PDE4D (1.00) | PDE4DSLC6A2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971901-B1 | PHTHALAZINONES | ALTANA PHARMA AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| US-6103718-A | Phthalazinones | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-08-15 | — | — | US | disclosed |