Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087294 | 0.97 | LCK (0.43) | LCKALDH1A1TSHRCHRM2LMNA | |
| SCHEMBL11040899 | 0.95 | LCK (0.44) | LCKALDH1A1TSHRCHRM2 | |
| SCHEMBL7770049 | 0.92 | LCK (0.46) | LCKALDH1A1TSHR | |
| SCHEMBL817850 | 0.92 | LCK (0.46) | LCKALDH1A1TSHR | |
| SCHEMBL8204150 | 0.90 | LCK (0.44) | LCKALDH1A1TSHR | |
| SCHEMBL28508921 | 0.87 | LCK (0.43) | LCKALDH1A1TSHR | |
| SCHEMBL28333383 | 0.87 | CHRM2 (0.46) | LCKALDH1A1TSHRCHRM2LMNA | |
| SCHEMBL11041212 | 0.84 | CHRM2 (0.42) | LCKALDH1A1TSHRCHRM2LMNA | |
| SCHEMBL63378 | 0.84 | CHRM2 (0.42) | LCKALDH1A1TSHRCHRM2LMNA | |
| SCHEMBL64537 | 0.84 | CHRM2 (0.42) | LCKALDH1A1TSHRCHRM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948182-A4 | METHOD FOR TREATING NEURONAL AND NON-NEURONAL PAIN | ZHUO MIN (CA) | 2009-08-19 | — | — | EP | claimed |
| EP-1948182-A1 | METHOD FOR TREATING NEURONAL AND NON-NEURONAL PAIN | ZHUO, Min (CA) | 2008-07-30 | — | — | EP | claimed |
| WO-2007041863-A1 | METHOD FOR TREATING NEURONAL AND NON-NEURONAL PAIN | ZHUO MIN (CA) | 2007-04-19 | — | — | WO | claimed |
| US-8124599-B2 | Method for treating neuronal and non-neuronal pain | FOREVER CHEER INTERNATIONAL LIMITED (HK) | 2012-02-28 | — | — | US | disclosed |