Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145836 | 1.00 | F10 (0.48) | F10DGAT1GRM2PI4K2ANR1I2 | |
| SCHEMBL4389189 | 0.91 | F10 (0.47) | F10DGAT1GRM2NR1I2 | |
| SCHEMBL7144367 | 0.90 | F10 (0.47) | F10DGAT1GRM2 | |
| SCHEMBL7144382 | 0.90 | F10 (0.47) | F10DGAT1GRM2 | |
| SCHEMBL4388083 | 0.89 | F10 (0.46) | F10DGAT1GRM2NR1I2 | |
| SCHEMBL4388077 | 0.89 | F10 (0.46) | F10DGAT1GRM2NR1I2 | |
| SCHEMBL7150928 | 0.89 | F10 (0.47) | F10DGAT1GRM2NR1I2 | |
| SCHEMBL1384927 | 0.89 | F10 (0.46) | F10DGAT1GRM2 | |
| SCHEMBL7150921 | 0.89 | F10 (0.47) | F10DGAT1GRM2NR1I2 | |
| SCHEMBL1651383 | 0.89 | F10 (0.46) | F10DGAT1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1420882-A | Substd. oxoazaheterocyclyl compounds | AVENTIS PHARM PROD INC (US) | 2003-05-28 | — | — | CN | claimed |
| JP-2003508353-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | claimed |
| CN-1420882-A | Substd. oxoazaheterocyclyl compounds | AVENTIS PHARM PROD INC (US) | 2003-05-28 | — | — | CN | disclosed |