Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3056366 | 0.90 | ADORA2A (0.65) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL5713516 | 0.89 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL3053641 | 0.89 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL3044761 | 0.89 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL7149427 | 0.89 | ADORA2A (0.67) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL3049495 | 0.89 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL3049355 | 0.89 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL3053117 | 0.88 | ADORA2A (0.61) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL28412423 | 0.87 | ADORA2A (0.68) | ADORA2AADORA1ADORA2BMEN1KMT2A | |
| SCHEMBL28416866 | 0.87 | ADORA2A (0.68) | ADORA2AADORA1ADORA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303272-A2 | BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| WO-2001097786-A2 | BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-12-27 | — | — | WO | disclosed |