Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 11/20 | 0.62 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.53 |
| ▸ | FPR3 | P25089 | 1/20 | 0.45 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144980 | 0.87 | CCR1 (0.61) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL7095156 | 0.87 | CCR1 (0.57) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL7002150 | 0.84 | CCR1 (0.51) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL7000591 | 0.83 | CCR1 (0.62) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL7000018 | 0.81 | CCR1 (0.53) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL6993588 | 0.80 | CCR1 (0.48) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL5064429 | 0.79 | PTGDR2 (0.79) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL6155923 | 0.79 | CCR1 (0.54) | CCR1PTGDR2TSHR | |
| SCHEMBL6758127 | 0.79 | CCR1 (0.54) | CCR1PTGDR2TSHR | |
| SCHEMBL6155917 | 0.79 | CCR1 (0.54) | CCR1PTGDR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326867-A2 | BRIDGED PIPERAZINE DERIVATIVES | Pfizer Products Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032901-A2 | BRIDGED PIPERAZINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2002-04-25 | — | — | WO | disclosed |