⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2111283 | 0.83 | HDAC8 (0.30) | — | |
| SCHEMBL9455886 | 0.77 | — | — | |
| SCHEMBL3394194 | 0.77 | — | — | |
| SCHEMBL3393659 | 0.74 | — | — | |
| SCHEMBL3672730 | 0.71 | POLB (0.36) | — | |
| SCHEMBL3393547 | 0.71 | — | — | |
| SCHEMBL2111397 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL3396396 | 0.70 | POLB (0.34) | — | |
| SCHEMBL10915767 | 0.70 | TSHR (0.33) | — | |
| SCHEMBL2111400 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226558-A2 | Chemical intermediates and methods for their preparation | Aktiebolaget Hässle (SE) | 1987-06-24 | — | — | EP | claimed |
| US-9040564-B2 | Stabilized composition | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-05-26 | — | — | US | disclosed |
| US-9040564-B2 | Stabilized composition | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-05-26 | — | — | US | disclosed |
| CN-101208090-B | Stabilized compositions | EISAI R&D MAN CO LTD | 2012-03-21 | — | — | CN | disclosed |
| US-8124780-B2 | Benzimidazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-8124780-B2 | Benzimidazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| CN-101160306-B | Benzimidazole compounds | EISAI R&D MAN CO LTD | 2011-11-02 | — | — | CN | disclosed |
| CN-101336240-B | Salt of sulfinyl benzimidazole compound, and crystal and amorphous form thereof | EISAI R&D MAN CO LTD | 2011-06-29 | — | — | CN | disclosed |
| US-20110009624-A9 | BENZIMIDAZOLE COMPOUNDS HAVING GASTRIC ACID SECRETION INHIBITORY ACTION | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20110009624-A9 | BENZIMIDAZOLE COMPOUNDS HAVING GASTRIC ACID SECRETION INHIBITORY ACTION | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-0268956-B2 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | EISAI CO LTD (JP) | 1998-04-15 | — | — | EP | disclosed |
| EP-0786461-A1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | Eisai Co., Ltd. (JP) | 1997-07-30 | — | — | EP | disclosed |
| EP-0654471-A1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and process for preparing the same | Eisai Co., Ltd. (JP) | 1995-05-24 | — | — | EP | disclosed |
| EP-0226558-B1 | Chemical intermediates and methods for their preparation | HAESSLE AB (SE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0484265-A1 | A process for the preparation of omeprazol | CENTRO GENESIS PARA LA INVESTIGACION, S.L. (ES) | 1992-05-06 | — | — | EP | disclosed |
| EP-0475456-A1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | Eisai Co., Ltd. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-5045552-A | Pyridine derivatives having anti-ulcerative activity | EISAI CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| US-4785113-A | 2,4-dichloro-3,5,6-trimethylpyridine | AKTIEBOLAGET HASSLE (SE) | 1988-11-15 | — | — | US | disclosed |
| EP-0268956-A2 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | Eisai Co., Ltd. (JP) | 1988-06-01 | — | — | EP | disclosed |
| EP-0226558-A2 | Chemical intermediates and methods for their preparation | Aktiebolaget Hässle (SE) | 1987-06-24 | — | — | EP | disclosed |