Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 14/20 | 0.76 |
| ▸ | F2 | P00734 | 11/20 | 0.76 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.76 |
| ▸ | F10 | P00742 | 10/20 | 0.76 |
| ▸ | F3 | P13726 | 5/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.61 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8120342 | 0.99 | F7 (0.75) | F7F2PRSS1F10F3 | |
| Hydrochloric Acid SCHEMBL8120348 | 0.99 | F7 (0.75) | F7F2PRSS1F10F3 | |
| SCHEMBL7146394 | 0.91 | F7 (0.62) | F7F2PRSS1F10F3 | |
| Hydrochloric Acid SCHEMBL8121789 | 0.90 | F7 (0.88) | F7F2PRSS1F10F3 | |
| Hydrochloric Acid SCHEMBL8128699 | 0.90 | F7 (0.88) | F7F2PRSS1F10F3 | |
| Hydrochloric Acid SCHEMBL7149307 | 0.90 | F7 (0.88) | F7F2PRSS1F10F3 | |
| SCHEMBL7144329 | 0.89 | F7 (0.77) | F7F2PRSS1F10F3 | |
| SCHEMBL7143824 | 0.87 | F7 (0.73) | F7F2PRSS1F10F3 | |
| SCHEMBL7148091 | 0.86 | F7 (0.55) | F7F2PRSS1F10F3 | |
| Hydrochloric Acid SCHEMBL7144104 | 0.85 | F7 (0.98) | F7F2PRSS1F10F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921116-B1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | EP | disclosed |
| US-6140353-A | USED AS MEDICAMENTS FOR THE TREATMENT AND/OR PREVENTION OF THROMBOSES, APOPLEXY, CARDIAC INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS OR AS ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |