Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 3/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311668 | 0.89 | DDB1 (0.40) | L3MBTL1DDB1CRBNHSD17B10MEN1 | |
| SCHEMBL23001009 | 0.76 | ACE (0.41) | ACEALDH1A1 | |
| SCHEMBL31293181 | 0.74 | DDB1 (0.39) | DDB1CRBNHSD17B10MEN1ALDH1A1 | |
| SCHEMBL5787292 | 0.73 | PDE4A (0.40) | DDB1CRBNHSD17B10MEN1ALDH1A1 | |
| SCHEMBL2017312 | 0.72 | POLB (0.44) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7391805 | 0.72 | NPC1 (0.44) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL15578408 | 0.71 | DDB1 (0.41) | DDB1CRBNACEMAPTSMN1; SMN2 | |
| SCHEMBL19777703 | 0.71 | PLA2G10 (0.33) | L3MBTL1DDB1CRBNACEPLA2G10 | |
| SCHEMBL19768572 | 0.71 | TP53 (0.34) | L3MBTL1DDB1CRBNPLA2G10PLA2G5 | |
| SCHEMBL17964241 | 0.71 | BRD4 (0.39) | L3MBTL1DDB1CRBNKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928790-B1 | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 2003-03-05 | — | — | EP | disclosed |