Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146601 | 1.00 | PRCP (0.38) | PRCPNOS2NOS3NOS1 | |
| SCHEMBL7140983 | 0.97 | PRCP (0.41) | PRCPNOS2NOS1 | |
| SCHEMBL7140989 | 0.97 | PRCP (0.41) | PRCPNOS2NOS1 | |
| SCHEMBL7138502 | 0.95 | PRCP (0.44) | PRCPNOS2NOS1 | |
| SCHEMBL7138506 | 0.95 | PRCP (0.44) | PRCPNOS2NOS1 | |
| SCHEMBL7135643 | 0.93 | PRCP (0.33) | PRCP | |
| SCHEMBL7135646 | 0.93 | PRCP (0.33) | PRCP | |
| SCHEMBL7140891 | 0.76 | — | — | |
| SCHEMBL7140897 | 0.76 | — | — | |
| SCHEMBL7138440 | 0.69 | PRCP (0.38) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966464-B1 | SUBSTITUTED 2,4-DIAMINOPYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-05-28 | — | — | EP | disclosed |
| US-6114330-A | BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0966464-A1 | SUBSTITUTED 2,4-DIAMINOPYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998039328-A1 | SUBSTITUTED 2,4-DIAMINOPYRIMIDINES | F.HOFFMANN-LA ROCHE AG (CH) | 1998-09-11 | — | — | WO | disclosed |