Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 20/20 | 0.79 |
| ▸ | PDE4A | P27815 | 8/20 | 0.79 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.79 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.79 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146863 | 1.00 | PDE4D (0.79) | PDE4DPDE4APDE4BPDE4CSLC6A2 | |
| SCHEMBL7146867 | 1.00 | PDE4D (0.79) | PDE4DPDE4APDE4BPDE4CSLC6A2 | |
| SCHEMBL7140704 | 0.88 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7140700 | 0.88 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7140709 | 0.88 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7146405 | 0.86 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CSLC6A2 | |
| SCHEMBL7146403 | 0.86 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CSLC6A2 | |
| SCHEMBL7146400 | 0.86 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CSLC6A2 | |
| SCHEMBL4116464 | 0.85 | PDE4D (0.71) | PDE4DPDE4APDE4BPDE4CSLC6A2 | |
| SCHEMBL4116468 | 0.85 | PDE4D (0.71) | PDE4DPDE4APDE4BPDE4CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971901-B1 | PHTHALAZINONES | ALTANA PHARMA AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| US-6103718-A | Phthalazinones | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-08-15 | — | — | US | disclosed |